Frankie Stein / Lilith Van Helscream (voice)

Jackson Jekyll / Holt Hyde / Operetta / Additional Voice (voice)

Clawdeen Wolf / Cleo de Nile (voice)

Abbey Bominable / C.A. Cupid / Clair / Additional Voices (voice)

Lagoona Blue / Headmistress Bloodgood (voice)

Draculaura (voice)

Clawd Wolf (voice)

Deuce Gorgon / Gil Webber / Thad (voice)

Howleen Wolf / Toralei Stripe (voice)

Ghoulia Yelps / Manny Taur / Sheriff / Additional voices (voice)

Heath Burns / Mr. Rotter / Goon #2 (voice)

Robecca Steam / Venus McFlytrap (voice)

Chad / Kid #1 (voice)

Gargoyle (voice)

Goon #1 (voice)

Narrator (voice)

Nefera De Nile (voice) (uncredited)

Tiki People (voice) (uncredited)