Mind Prey is an adaptation of the John Sandford mystery novel of the same name, featuring Sandford's famous detective Lucas Davenport. Andi Manette (Sheila Helley), a well respected psychiatrist, and her two daughters have been kidnapped and detective Lucas Davenport (Eriq La Salle) is about to meet his ultimate nemesis in their sadistic captor, John Mail (Titus Welliver). Davenport and Mail both have a penchant for computer games and gaming culture. Their shared interest helps Davenport to understand and guess the kidnapper's next move, but the victims are put in further danger when Mail forces Davenport into a cruel and insane cat-and-mouse game.