The successful royal doctor Yoo Sepoong becomes entangled in a conspiracy and is kicked out of the palace. He ends up in Sorak Village and encounters Gye Jihan, the so-called crazy doctor, and the widow Eunwoo. He starts a new career treating heartsick patients, finding the cause of their heartbroken feelings and providing remedies for happiness.

Season 1 of House of the Dragon premiered on August 1, 2022.