Rob has been living on supplemental oxygen and urgently needs a double lung transplant. After no fewer than 17 heart surgeries over the years, Joe has defied the odds, but now he must have a heart and liver transplant in order to survive.

Dying of heart failure and COVID-19, Reverend Kenyatta Braxton prays for a heart and double lung transplant. Recovered addict Jeff hopes a new liver can save him so he can help raise his granddaughter.

At Vanderbilt University Medical Center, heart transplant patient Krystal goes into cardiac arrest while waiting to be listed for a donor heart. Carlos, a young father in desperate need of a new kidney, finds a life-saving friend in live donor Adam.