After the nuclear apocalypse, the world’s chosen elite survive in secure Outposts created by the mysterious Cooperative. On the American West Coast, Ms. Wilhemina Venable and Ms. Miriam Mead run Outpost Three with an iron fist. The unexpected arrival of Michael Langdon, a Cooperative representative determined to save society with a secret paradise, throws their order into chaos. However, underneath the surface of humanity’s salvation lies a battlefield for the final conflict between good and evil.
The few remaining Salem descendants are under assault by forces of ignorance and hate. The young witches seek refuge at Miss Robichaux's Academy in New Orleans, including new arrival, Zoe, who harbors a terrifying secret of her own. Fiona, a Supreme Witch with unimaginable powers, is determined to protect the Coven, but her obsessive quest for immortality will lead her to cross paths with a voodoo queen and a murderous slave owner cursed with eternal life.
When the Harmon family relocates to a stately mansion in Los Angeles, disturbing secrets start enveloping each of their lives. As they slowly learn about the mysterious and deadly history of their new house, psychiatrist Ben, Vivien and their teenage daughter Violet find themselves surrounded by all manner of menacing spirits, living and dead.