Leonard Hofstadter (279 Episodes)

Sheldon Cooper (279 Episodes)

Penny (279 Episodes)

Howard Wolowitz (279 Episodes)

Rajesh Koothrappali (279 Episodes)

Bernadette Rostenkowski (221 Episodes)

Amy Farrah Fowler (217 Episodes)

Stuart Bloom (84 Episodes)

Debbie Wolowitz (voice) (40 Episodes)

Wil Wheaton (17 Episodes)

Beverly Hofstadter (16 Episodes)

Bert Kibbler (15 Episodes)

President Siebert (13 Episodes)

Zack Johnson (11 Episodes)

Halley Wolowitz (voice) (10 Episodes)

Anu (9 Episodes)

Denise (8 Episodes)

Stephen Hawking (7 Episodes)

Althea (6 Episodes)

Richard Williams (6 Episodes)

Mike Rostenkowski (6 Episodes)

Michael J. Massimino (6 Episodes)

Janine Davis (6 Episodes)

Arthur Jeffries (6 Episodes)

Claire (5 Episodes)

Eric Gablehauser (5 Episodes)

Announcer (voice) (2 Episodes)

Wyatt Teller (5 Episodes)

Dimitri (5 Episodes)

Alex Jensen (4 Episodes)

Dave Roeger (voice) (1 Episodes)

Kurt (3 Episodes)

LeVar Burton (3 Episodes)

Ramona Nowitzki (3 Episodes)

Computer (voice) (2 Episodes)

Ruchi (3 Episodes)

Dave Gibbs (3 Episodes)

Security Guard (2 Episodes)

Stephanie Barnett (3 Episodes)

Ira Flatow (2 Episodes)

Glen (2 Episodes)

Captain Sweatpants (uncredited) (2 Episodes)

Georgie Cooper (3 Episodes)

Mrs. Fowler (3 Episodes)

Larry Fowler (3 Episodes)

Kevin Campbell (3 Episodes)

Greg Pemberton (3 Episodes)

Eric (2 Episodes)

David Underhill (2 Episodes)

Mikayla (2 Episodes)

Professor Crawley (2 Episodes)

Sandy (2 Episodes)

Angela Page (2 Episodes)

Glenn (2 Episodes)

Mrs. Latham (2 Episodes)

Charlotte (2 Episodes)

Jeremy (2 Episodes)

Alicia (2 Episodes)

Cheryl (2 Episodes)

Chen (2 Episodes)

Kevin (2 Episodes)

Alice (2 Episodes)

Dan (2 Episodes)

Santa Claus (2 Episodes)

Minister (1 Episodes)

Maria (2 Episodes)

Waiter (2 Episodes)

Alfred Hofstadter (2 Episodes)

Mrs. Fowler (1 Episodes)

Hostess (1 Episodes)

Emily (2 Episodes)

Self (2 Episodes)

Waiter (2 Episodes)

Dale (2 Episodes)

Jimmy Speckerman (1 Episodes)

Analeigh Tipton (1 Episodes)

Bill Nye (2 Episodes)

Neil deGrasse Tyson (2 Episodes)

Missy Cooper (2 Episodes)

Karen (2 Episodes)

Dr. Graybel (2 Episodes)

Mrs. Petrescu (2 Episodes)

Kevin Smith (2 Episodes)

Jess (2 Episodes)

Marissa Johnson (2 Episodes)

Ellen DeGeneres (2 Episodes)

George F. Smoot (2 Episodes)

Octavia (1 Episodes)

Self (1 Episodes)

Catherine Millstone (1 Episodes)

Officer Hackett (1 Episodes)

Elizabeth Plimpton (1 Episodes)

Self (1 Episodes)

Self (1 Episodes)

Vicki (1 Episodes)

Mike (1 Episodes)

Emma (1 Episodes)

Angelo (1 Episodes)

Christy Vanderbel (1 Episodes)

Professor Laughlin (1 Episodes)

Abby (1 Episodes)

Dance Instructor (1 Episodes)

Professor Goldfarb (1 Episodes)

Doug (1 Episodes)

Patty (1 Episodes)

Oliver Lorvis (1 Episodes)

Jeanie (1 Episodes)

Self (1 Episodes)

Self (1 Episodes)

Toby Loobenfeld (1 Episodes)

Lalita Gupta (1 Episodes)

Photographer (1 Episodes)

Older Indian Man (1 Episodes)

Nathan Fillion (1 Episodes)

Hostess (1 Episodes)

Cindy (1 Episodes)

Zombie (1 Episodes)

Mitchell (1 Episodes)

Security Guard (1 Episodes)

Security Guard #2 (voice) (1 Episodes)

Josh Wolowitz (1 Episodes)

Caller (voice) (1 Episodes)

Gwen (1 Episodes)

Chelsea (1 Episodes)

Casting Assistant (1 Episodes)

Alien (voice) (1 Episodes)

Alien #2 (voice) (1 Episodes)

Tech Support (voice) (1 Episodes)

Tech Support Recording (voice) (1 Episodes)

Receptionist (1 Episodes)

Mandy Chao (1 Episodes)

Candidate #1 (1 Episodes)

Candidate #2 (1 Episodes)

Candidate #3 (1 Episodes)

Natalie (1 Episodes)

Grace (1 Episodes)

Attractive Red Head (1 Episodes)

Kenny Fitzgerald (1 Episodes)

Paramedic (1 Episodes)

Grace (1 Episodes)

Scientist (1 Episodes)

Pizza Delivery Guy (1 Episodes)

Woman (1 Episodes)

Dr. Gunderson (1 Episodes)

Scientist (1 Episodes)

Self (1 Episodes)

Elon Musk (1 Episodes)

Travis (1 Episodes)

Trent Monaco (1 Episodes)

Siri (voice) (1 Episodes)

Dr. Gallow (1 Episodes)

Connie Tucker (1 Episodes)

Self (1 Episodes)

Glenn the Maitre D' (1 Episodes)

Customer (1 Episodes)

Airport Pedestrian (1 Episodes)

Tim (1 Episodes)

Andre (1 Episodes)

Trevor (1 Episodes)

Susan Teller (1 Episodes)

Randall Teller (1 Episodes)

Marty (1 Episodes)

The Flash (1 Episodes)

Daniel (1 Episodes)

Christopher (1 Episodes)

Jeff (1 Episodes)

Issabella (1 Episodes)

Theodore (1 Episodes)

Doug (1 Episodes)

Rebecca (1 Episodes)

Dr. Bernstein (1 Episodes)

Dr. Harris (1 Episodes)

Dr. Zane (1 Episodes)

Maria (1 Episodes)

Marta (1 Episodes)

Travis (1 Episodes)

Kenneth (1 Episodes)

Ms. Davora (1 Episodes)

Voicemail (voice) (1 Episodes)

Salesperson (1 Episodes)

Wardrobe Person (1 Episodes)

Flight Attendant (voice) (1 Episodes)

Dr. Dreyfus (1 Episodes)

Eric (1 Episodes)

Yvette (1 Episodes)

Jesse (1 Episodes)

Lizzy (1 Episodes)

Student (1 Episodes)

Nell (1 Episodes)

Chinese Leonard (1 Episodes)

Oliver (1 Episodes)

Self (1 Episodes)

Todd (1 Episodes)

Self (1 Episodes)

Venkatesh Koothrappali (1 Episodes)

Chinese Sheldon (1 Episodes)

Jan (1 Episodes)

Sarah (1 Episodes)

Joyce Kim (1 Episodes)

Young Man (1 Episodes)

Cole (1 Episodes)

Summer (1 Episodes)

Waitress (1 Episodes)

News Announcer (voice) (1 Episodes)

Kathy O'Brien (1 Episodes)

Dan (1 Episodes)

Blaine (1 Episodes)

Lourdes (1 Episodes)

Ground Controller (voice) (1 Episodes)

Mildred (1 Episodes)

Skeeter (1 Episodes)

Judge J. Kirby (1 Episodes)

Sebastian (1 Episodes)

Dry Cleaner (1 Episodes)

Reverend White (1 Episodes)

Stan (1 Episodes)

Woman (1 Episodes)

Joey (1 Episodes)

Mrs. Gunderson (1 Episodes)

Louie (1 Episodes)

Ho-Jun (1 Episodes)

Angela (1 Episodes)

Laura (1 Episodes)

Sandy (1 Episodes)

Self (1 Episodes)

Lakshmi Choudry (1 Episodes)

Phil (1 Episodes)

Mrs. Rostenkowski (1 Episodes)

Jonathan (1 Episodes)

Jimmy (1 Episodes)

Officer Reynolds (1 Episodes)

Clerk (1 Episodes)

Dr. Sanders (1 Episodes)

Son (1 Episodes)

Joy (1 Episodes)

Elsie (1 Episodes)

Officer Shin (1 Episodes)

Nurse in Biohazard Suit (1 Episodes)

Dispatcher (voice) (1 Episodes)

Claire (1 Episodes)

Aaron (1 Episodes)

Professor Rothman (1 Episodes)

Girl #1 (1 Episodes)

Tom (1 Episodes)

Lana (1 Episodes)

Danielle (1 Episodes)

Police Officer (1 Episodes)

Man (1 Episodes)

Self (1 Episodes)

Todd Zarnecki (1 Episodes)

Jeremy (1 Episodes)

Dr. Schneider (1 Episodes)

Car Thief #1 (1 Episodes)

Girl #2 (1 Episodes)

Professor Sharpe (1 Episodes)

Moviegoer (voice) (1 Episodes)

Nolan (1 Episodes)

Ainsley (1 Episodes)

Denise (1 Episodes)

Rose Lady (1 Episodes)

Lillian (1 Episodes)

Joan (1 Episodes)

Car Thief #2 (1 Episodes)

Gretchen (1 Episodes)

Justin (1 Episodes)

Clerk (1 Episodes)

Russian Mission Control (voice) (1 Episodes)

Chauffeur (1 Episodes)

Guy (1 Episodes)

Bill Gates (1 Episodes)

Bellman (1 Episodes)

Sunny Morrow (1 Episodes)

Tour Guide (1 Episodes)

Greg (1 Episodes)

Leslie (1 Episodes)

Waiter (1 Episodes)

Tam Nguyen (1 Episodes)

Dr. Park (1 Episodes)

Andrea (1 Episodes)

Colin (1 Episodes)

Sheldon Cooper (1 Episodes)

Georgie Cooper (1 Episodes)

Judge (1 Episodes)

Mark Hamill (1 Episodes)

Dr. Lee (1 Episodes)

Cynthia (1 Episodes)

Chad (1 Episodes)

Brenda (1 Episodes)

Nathan (1 Episodes)

Andy (voice) (1 Episodes)

Neil (1 Episodes)

Joe Manganiello (1 Episodes)

Kareem Abdul-Jabbar (1 Episodes)

William Shatner (1 Episodes)

Danny (1 Episodes)

Darren (1 Episodes)

Bebe (1 Episodes)

Woman #1 (1 Episodes)

Woman #2 (1 Episodes)

Woman #3 (1 Episodes)

Woman #4 (1 Episodes)

Woman #5 (1 Episodes)

Maritza (1 Episodes)

Terry (1 Episodes)

Mitch (1 Episodes)

Reporter #2 (1 Episodes)

Reporter #1 (1 Episodes)

Reporter #3 (1 Episodes)

Sarah Michelle Gellar (1 Episodes)

Dmitri (1 Episodes)

Martha (1 Episodes)

Marcus (1 Episodes)

Wendell (1 Episodes)

Cynthia (1 Episodes)

Neil Gaiman (1 Episodes)

Grant (1 Episodes)

Robert Wolcott (1 Episodes)

Bartender (1 Episodes)

Nicholas (1 Episodes)

Pit Boss (1 Episodes)

Croupier (1 Episodes)

Hostess (1 Episodes)

Earl (1 Episodes)

Jenna (1 Episodes)

Tom (1 Episodes)

Model (1 Episodes)

Rebecca (1 Episodes)

Denny (1 Episodes)

Mr. Spock (voice) (1 Episodes)

Roberta (1 Episodes)

Five Year Old (1 Episodes)

Stranger (1 Episodes)

Nurse (1 Episodes)

Man (1 Episodes)

Toby (1 Episodes)

Kathleen (1 Episodes)

Marta (1 Episodes)

Letty (1 Episodes)

Margaret (1 Episodes)

Greg (1 Episodes)

Bob (1 Episodes)

Linda (voice) (1 Episodes)

Woman (1 Episodes)

Kwame (1 Episodes)

Frances H. Arnold (1 Episodes)

Kip Thorne (1 Episodes)

Woman #6 (1 Episodes)

Woman #7 (1 Episodes)

Woman #8 (1 Episodes)

Little Girl (1 Episodes)

Carl XVI Gustaf of Sweden (1 Episodes)

Halley Wolowitz (1 Episodes)

Michael Wolowitz (1 Episodes)

Announcer (1 Episodes)

Daniel Westling (1 Episodes)

Guy at the Movies (uncredited) (1 Episodes)

Howie Mandel (1 Episodes)

Comic Book Store Customer (uncredited) (1 Episodes)

Eye Rolling Girl Student (uncredited) (1 Episodes)

Library Graduate Student (uncredited) (1 Episodes)

Officer Hernandez (1 Episodes)

Man (1 Episodes)

Woman (1 Episodes)

Older Gentleman (1 Episodes)

Roy (1 Episodes)

Stadium Announcer (voice) (1 Episodes)

American Shopper (uncredited) (1 Episodes)

Employee (1 Episodes)

Bike Messenger (uncredited) (1 Episodes)

Dennis Kim (1 Episodes)

Cheesecake Factory Patron (1 Episodes)

Brent Spiner (uncredited) (1 Episodes)