As a meth epidemic sweeps through the Golden Triangle, police investigate the operation’s rumored leader, Xaysana Keopimpha, but find themselves at the mercy of complex hierarchies within the syndicate.

After thirteen sailors are executed on a ship along the Mekong River, a Chinese task force is granted special permission to lead a manhunt across the Golden Triangle for suspected kingpin and merciless water taxman Naw Kham.

As heroin devastates the streets of 1970s New York, DEA agents team with Thai authorities to bring down Khun Sa, the criminal mastermind controlling 70% of Burma’s global drug trafficking trade.