A living island created by Dr Von Reichter begins making its way to Meridina harbour. It is programmed to explode once it arrives because he's tired of Jose's many failures and wants to wipe the slate clean.
Jose builds a bunch of mechanical animals and starts his own circus, The Greatest Show In Meridiana. Suspicious, Cybersix goes to the circus, only to be captured.
Von Riecher gifts Jose a strange egg that hatches into a soul-absorbing floating eye. Jose takes the eye to the city and soon the entire population, except for Cybersix, is soulless.
After being bitten by a wolfman Lucas finds himself getting hairier and becomes fascinated by the new teacher. Cybersix resents her influence over him but she's too busy fighting the wolfwoman Dr. Von Reichter has sent to hunt her.
Lori bumps into Jose and accidentally gets her CD switched for the CD-ROM he's using to program his tunneling robot that's going to dig into the city's treasury.
Jose tries to hire a detective to help him capture Cybersix. When he refuses, Jose kidnaps his sister and will only return her in exchange for Cybersix.
High school biology teacher Lucas Amato finds a tube with a glowing green ooze and takes it home with him. The next night a woman named Cybersix visits Lucas to retrieve the ooze called Sustenance. But before she has a chance to get it, a big strange man breaks into Lucas's apartment.