Kazuo Tengan's motives for masterminding the Final Killing Game are revealed as Ryota Mitarai decides to put an end to despair, by brainwashing all of humanity to sacrifice all negative emotions and unconditionally believe in hope. Makoto Naegi, Aoi Asahina and Kyosuke Munakata try to stop him, but their efforts are impeded by the brainwashed Future Foundation.
Leaving behind her notebook, Kyoko Kirigiri reveals the truth behind the Final Killing Game, leaving Makoto Naegi to test out his late friend's theory, only to be shocked by what he sees. Meanwhile, Juzo Sakakura decides to bring an end to this dreaded game in order to save Kyosuke Munakata.
Following Kyoko Kirigiri's death, Makoto Naegi resolves to bring an end to the Final Killing Game and clashes with Kyosuke Munakata, fighting for whose hope is stronger. However, a recent, shocking revelation about Chisa Yukizome has driven Kyosuke into insanity and despair.
Betrayals are committed as Ruruka Ando struggles to survive and the traitor is close to being revealed. Monaca Towa's prophecy comes true when Kyoko Kirigiri's NG code is violated, because of Makoto Naegi. To bring an end to this dreadful game of despair, Kyosuke Munakata decides it's time to decide whose hope is better: his or Makoto's.
Koichi Kizakura recalls his reasons for staying with Kyoko Kirigiri, who works to uncover the truth behind Sonosuke Izayoi's murder. But just being at the crime scene is dangerous enough itself. Meanwhile, Byakuya Togami looks for a way to break the Future Foundation out of the building, but certain obstacles prevent him from reaching that goal.
Komaru Naegi and Toko Fukawa confront Monaca Towa in the hopes of putting the Final Killing Game to an end, but things take a turn for the worst when the second Junko Enoshima reveals that a survivor from the Killing School Life will die because of Komaru's brother.
Monaca Towa continues using her puppet to fool the Future Foundation members, but Kyoko Kirigiri's just one step away from finding the truth, especially with all the clues she's gathered.
Seiko Kimura and Ruruka Ando's past comes to light as the two recall how their friendship broke apart.
Kyoko Kirigiri decides it's time for her to put her detective skills to work, and goes to the boardroom to investigate.
Monokuma's twisted game continues while Makoto tries to restore what little balance he can to the Future Foundation.
Monokuma reveals the rules of his new "Monokuma Hunter" game.
Makoto Naegi falls under scrutiny as the battle between the Future Foundation and the Remnants of Despair rages on!
