The war betwen Ajin terrorist Satou and Ajin Administrative Committee has been escalating with Satou declaring a public assassination attempt on 15 Ajin-related VIP, an action Satou calls "purging." The final confrontations between Ajin and the Japanese goverment, as well as between Satou and Kei Nagai, are about to begin.

A Student named Kei Nagai, who discovers he is an "Ajin" when he is fatally wounded in a traffic accident. In the world of Ajin, a small number of humans possess extreme regenerative abilities that trigger upon death or mortal infury, allow them to completely recover from their woulds in a matter of seconds. Kei, who wants no part in the emerging Ajin-human conflict. Agree with Japanese govermental againts to fight against Satou in exchange for his freedom from government experimentation.

Season 0 of House of the Dragon premiered on May 6, 2016.