Violence escalates out of control and lives are destroyed as the walls close in around Aureliano, Spadino and those they love.

Discovering the truth, Spadino sets himself on a collision course with Manfredi. Alice comes to a fraught decision about Cinaglia.

In the aftermath of the shooting, Aureliano and Spadino scramble to salvage their alliance. Cardinal Nascari tries to break Cinaglia's grip on him.

Spadino faces a renewed threat to his power. Cinaglia tries to back Cardinal Nascari into a corner. Nadia and Angelica learn the ropes in north Rome.

Ambitious for yet more power, Aureliano and Spadino consolidate control of their alliance and turn their eyes to new turf: north Rome.

Samurai, Cinaglia and Badali scheme to cash in on the Vatican's Jubilee celebration while Spadino forms a chilling plan to pull Cinaglia's strings.