Season 2 of House of the Dragon premiered on .

The first season follows the lives of surgical interns and resident doctors of Sanjeevani. The show starts off with introduction of 5 interns Dr. Anjali Gupta who also happens to be Dr. Shashank's daughter from the prequel, Dr. Armaan Malik, Dr. Riddhima Gupta, Dr. Atul Joshi, and Dr. Sapna Shah. Dr. Shashank continues to play an important role in this sequel of Sanjivani as the head of the hospital and father of Riddhima and Anjali. Armaan and Riddhima start to fall in love after a rough start, Atul falls in love with Anjali who is Riddhima's sister. Dr. Sapna Shah Gets Married and leaves Sanjeevani. Three new Interns Enter: Dr. Rahul Garewal, Dr. Muskaan Chadda, and Dr Nikita Malhotra. Muskaan and Rahul's family decided their marriage but they didn't agree. Muskaan falls for Armaan and Rahul befriends Riddhima. Nikita turns out to be Armaan's and Rahul's college friend. Later on Muskaan and Rahul fall in love however they break up due to difficulties. Nikita falls for Dr. Abhimanyu Modi a senior doctor. Season one ended on a cliffhanger showing Riddhima and Armaan getting shot in a shootout right after they get engaged and Abhimanyu's estranged wife Jiah returns.