20-year-old Lauren Spierer goes for a night out with friends in June 2011; the gorgeous college coed has never been seen since.

32-year-old Rebecca Zahau seemed to have it all until she's found dead in a multi-million dollar mansion hanging from a balcony under bizarre circumstances; police rule her death a suicide, but some aren't buying it.

College student Elisa Lam checks into a Los Angeles hotel -- but never checks out. The last known images of the young tourist are from the hotel's elevator security camera. Later, her naked body is found floating face-up in the hotel's rooftop water tank.

Beautiful mom Michelle Parker appears on an episode of "The People's Court", fighting with her ex-fiancé over a luxury diamond engagement ring; but hours after that episode airs Michelle mysteriously vanishes.

A family camping trip to Timber Creek Campground in the remote Idaho mountains turns into something out of a horror movie when 2-year-old DeOrr Kunz disappears; at first it looks like he may have been abducted, until other disturbing theories start to emerge.

Newlyweds Jessica and Matthew Boynton seems like the picture-perfect couple until the young mother is found unresponsive and covered in blood.

5-year-old Haleigh Cummings mysteriously disappears overnight from her home near Jacksonville, Florida, after her dad's girlfriend puts her to bed. Was Haleigh abducted or did something else happen?