Owed a lot of money by a man who has no cash, Bowie makes him an offer for his land in New Orleans, and we learn the origin of some of the street names there.
At the President's urgent request, Bowie guides a doctor to a Choctaw village to cure a sick boy, only to discover that the doctor is an inexperienced youth fresh out of medical school.
Bowie becomes the blood brother of an Apache tribe whom he believes know the location of the lost silver mine he has been searching for, but discovers that his old friend has done the same thing with a tribe of Comanches who also know the secret.
Bowie manages to get back across the border into Texas by signing on as an Englishman's valet, but then the pair are attacked by both outlaws and Comanches.
When Bowie solicits help from his cousin after being swindled by a group of good-natured hillbillies, he almosts gets the poor fellow married to one of them.
Bowie comes to the aid of naturalist Johnny Appleseed, who has been captured by criminals who think that the riches in the ground he talks about are buried treasure.
Bowie gets a lead on the location of the lost silver mine of the Apaches, but both hostile Apaches and Mexican officials make it difficult for him to follow it up.
When Bowie and his brother learn that the bank they own in New Orleans is being robbed, they try to keep the thieves from getting away by using the city's signaling cannon.
When a hillbilly puts up his daughter as a stake in a poker game, Bowie goes along with the idea to teach him a lesson, and then decides to send her to a finishing school to become a lady.
Bowie and his pirate friend Jean Lafitte, attempting to rescue a U.S. ambassador who has been captured by revolutionary forces in Mexico, take refuge in an inn at Christmastime.
While on his way to inform the authorities of a plot to misuse the labor of prisoners, Bowie is trapped in a warehouse and attacked by a whip-wielding stranger.