Natasha Lyonne hosts Saturday Night Live on May 21, 2022 with musical guest Japanese Breakfast.

Selena Gomez hosts Saturday Night Live on May 14, 2022 with musical guest Post Malone.

Benedict Cumberbatch hosts Saturday Night Live on May 7, 2022 with musical guest Arcade Fire.

Lizzo hosts and performs as musical guest on Saturday Night Live on April 16, 2022.

Jake Gyllenhaal hosts Saturday Night Live on April 9, 2022 with musical guest Camila Cabello.

Jerrod Carmichael hosts Saturday Night Live on April 2, 2022 with musical guest Gunna.

Zoë Kravitz hosts Saturday Night Live on March 12, 2022 with musical guest Rosalía.

Oscar Isaac hosts Saturday Night Live on March 5, 2022 with musical guest Charli XCX.

John Mulaney hosts Saturday Night Live on February 26, 2022 with musical guest LCD Soundsystem.

Willem Dafoe hosts Saturday Night Live on January 29, 2022 with musical guest Katy Perry.

Will Forte hosts Saturday Night Live on January 22, 2022 with musical guest Måneskin.

Ariana DeBose hosts Saturday Night Live on January 15, 2022 with musical guest Bleachers.

Actor and People's sexiest man of 2021 hosts.

Billie Eilish hosts and performs as the musical artist. Kate McKinnon returns presenting the CDC Players.

Simu Liu hosts Saturday Night Live on November 20, 2021 with musical guest Saweetie.

Jonathan Majors hosts Saturday Night Live on November 13, 2021 with musical guest Taylor Swift.

Kieran Culkin hosts Saturday Night Live on November 6, 2021 with musical guest Ed Sheeran.

Jason Sudeikis hosts Saturday Night Live on October 23, 2021 with musical guest Brandi Carlile.

Rami Malek hosts Saturday Night Live on October 16, 2021 with musical guest Young Thug.

Kim Kardashian West hosts Saturday Night Live on October 9, 2021 with musical guest Halsey.

Owen Wilson hosts Saturday Night Live on October 2, 2021, with musical guest Kacey Musgraves.