With the aftershocks of Sept. 11 and man named Barry , who lost his wife that day and then his job soon after. The man lashes out at her former boss an employment-agency owner. Blaming her for his wife's death and his own failure to find a job, Barry kidnaps the woman for ransom.Then he demands the money be exchanged at a bookstore, but when the cash is delivers Berry is provoked and takes the store's patrons hostage. Among them is Samantha,and given Jack's affection for her complicates the negotiations.
The team find themselves up against the ropes as multiple mysteries arise in the case of a boxer. Dante Jones disappears moments before a bout with a $500,000 purse that which could have made him a title contender. Jack suspects it's stunt, but Vivian, a Jones fan, can't believe that the charity-loving, straight-arrow fighter would go doewn that low road. The search goes in a new direction when his younger brother who he is always bailing out of trouble, vanishes. Then it's learned he has made 2 million dollers in the past five years,but he only has $6000 in his bank account.
Delia , a television reporter, disappears in the middle of the investigation of a nightclub owner who is a suspected drug dealer. They also discovers that Delia was working on the case of a murderer on death row who she thought was innocent, and who might be linked to an assistant district attorney working with Jack on the case.
Chet Collins has been searching for his son since the boy was kidnapped four years earlier on a camping trip, and is the one case that Jack has never been able to forget. When Chet disappears, leaving behind only his wedding ring and the mountains of debt he had accumulated in his search, Jack will go to any lengths to find Collins and save him from himself.
Jack and the team search for a pregnant woman, Kathy Dobson, who disappeared from a hospital before being told that she has serious complications. As the detectives race against time to find Kathy, their investigation gradually reveals that Kathy's seemingly happy life actually hasn't been going very well. She is eight-and-a-half months pregnant and, under the tight control of her husband Paul, has withdrawn from her family and friends. Paul's brother Ritchie, who has been following Kathy and providing Paul with addresses she visits, lists a woman who may be affiliated with an ""underground railroad"" that helps battered women. When the team members find the woman, they learn that she has been assaulted by Paul—but she still refuses to lead them to Kathy.
Annie Miller disappears on her way to school. The group looks into her disappearance, with their suspects ranging from the local mayor, to Annie's godfather, all the way to a young man working for the father of her best friend. Twenty-four hours after Annie's disappearance, her best friend Siobhan Arintero also vanishes, leaving only a collection of videos to help find the two girls.