Two high-ranking Xindi offer to stop the launch of their superweapon if Archer can prove they've been manipulated. Meanwhile, the crew mourns their lost mates.
The fate of Enterprise is in Dr. Phlox's hands as the rest of the crew must be induced into a coma in order to survive a trans-dimensional disturbance.
When Trip suffers a catastrophic injury, his only hope for survival is a transplant from a "mimetic symbiont" which Phlox grows from one of his exotic creatures.
When a settlement of humans living a 19th-century Western lifestyle is discovered on a Delphic Expanse planet, Archer and crew set out to learn how they got there.
A spatial distortion leaves Archer unable to form any new long-term memories. Years in the future, he wakes up one morning and is stunned to learn the outcome of the human-Xindi conflict.
Archer, Reed and Major Hayes infiltrate a Xindi-Sloth industrial colony to learn more about the weapon of mass destruction that will be used against Earth.
When Enterprise responds to a distress call from a Vulcan ship stranded in the Delphic Expanse, Archer and his boarding team are attacked by insane zombie-like Vulcans.
On a mission to investigate an abandoned Xindi vessel on a jungle planet, Archer, Reed and Hoshi succumb to a virus that mutates them into a primal life form.