Frank and Garrett quarrel when Garrett refuses to walk back a quote he provided to a local newspaper. Danny and Baez discover a connection to a feud between local residents and city-sponsored hotels for the homeless while investigating a murder. Anthony is mistaken for a mafioso. Eddie pressures Jamie to take a love language quiz.
Business becomes personal for Frank and his team when Baker is assaulted on the street, as well as for Erin, when she asks her ex-husband to represent a defendant she’s prosecuting. Eddie wonders if she’s being too stubborn after she publicly undermines one of Jamie’s decisions at work. Danny and Baez investigate the attempted murder of a couple with big secrets.
Frank asks Erin to liaise between him and Governor Mendez regarding policy reform he privately backs, but can’t publicly support, because it goes against police rank and file. Danny and Baez become enmeshed in the world of competitive gaming when a high-profile video game streamer is murdered. Eddie and Witten suspect a live-in nanny is being abused after she approaches them on the street for help.
Baez confides in Danny and asks for his help in proving her innocence after she finds a corpse in her front yard. Erin struggles to find a peaceful solution when she receives harsh case notes from her boss. Jamie and Eddie butt heads over the handling of a young cop’s punishment. Frank makes his whole team attend therapy after Gormley exhibits troubling behavior.
Erin tries not to feel overpowered as her new boss shadows her at work just as she's trying to get a nervous eye-witness to reveal the identity of who shot her boyfriend. The serial killer who previously held Danny and Baez hostage resurfaces, and when Jaime arrests an intrusive reporter who appears at a series of store lootings, it leads to a standoff between Frank and the Attorney General.
Amidst a shifting political climate, Frank goes head to head with City Council Speaker Regina over protests against police brutality. Jamie and his nephew Joe work together to locate Danny and Baez when they go missing while searching for a killer. Eddie steps up to help an abrasive woman find her father's body after it was misplaced.