Scott receives some disturbing news that may mean the end of Comedy Bang! Bang! forever, but before the end, old chums Lord Andrew Lloyd Webber and Fabrice Fabrice stop by to wish the gang goodbye.
Reggie Watts returns to the show just in time to try to prevent a disaster; Weird Al has a surprising announcement; Adam Scott tries to give Scott some assistance.
Scott is excited to spend Thanksgiving celebrating with the Comedy Bang! Bang! crew, but a group of outsiders could disrupt his plans; Mike Colter discloses a shocking revelation; teacher Joe Bongo discusses his extra-curricular activities.
Scott's estranged family visits; Ben Folds discusses his new start-up business; Weird Al shows his new sports documentary; world-traveler Martin Moreland visits.
Scott and Weird Al throw a party that gets a little out of control; Krysten Ritter plays her favorite party game; author Gail Summercat gives tips to women in the workplace.
When Scott leaves the show for a new opportunity, Jason Mantzoukas takes over as special substitute host and his first guest ends up being Scott; legendary soul singer Donny Gary.
The studio prepares for a calm Halloween, but unbeknownst to Scott and the crew, they are being haunted by a ghoulish spirit; Gillian Jacobs gets a free cocktail; Scott shows off his latest film role.
The crew is visited by some American heroes to try to bring the country back to its moral foundations; Kaley Cuoco finalizes her will; lifestyle coach Karen helps Scott style his inside.
Joe Jonas demonstrates his unusual cellphone replacement; Scott arranges a memorial service for an old friend; Maxwell Keeper discusses his workplace; and a sneak peek at Scott's movie.
Aubrey Plaza attempts to seduce Scott; and later, a stranger transports Scott and Weird Al to a different era in time. Also, an intrepid adventurer regales all with his sexual exploits.
T-Pain, Scott and Weird Al collaborate on a song; and Melvin Alberts talks about being abducted by aliens. Later, Scott's scientific breakthrough allows him to get more stuff done; and Weird Al previews his new foodie-TV show.
Tegan and Sara riff on their songwriting process, while Scott suspects there's something odd about the new intern. Also, the audience receives acting tips from a surprise guest.
Tony Hale throws out the ceremonial first pitch, while Scott pranks the crew. Also, a preview of Scott's offbeat new game show, "You Made Your Bed, Now Lie in It."
In the Season 5 premiere, Weird Al Yankovic signs on as band leader and guest Kevin Bacon leads a tour of Kevin Town. Also, a leprechaun hassles Scott.