After Will fires Joanna for sleeping with Julian, she uncovers video tapes of Vivian's therapy sessions. Working with the FBI, Julian wears a wire to gain evidence against Audrey. Edward turns himself in for the murder of Kimberly Yaeger. With Haverstock's help, Wyatt is released from prison and confronts Sofia. Mia takes Joanna's advice and donates her bone marrow to her birth father.
Robert begins to suspect Joanna's true motives for coming back into their lives and flies her mother, Beverly, to New York, to help uncover the truth. Meanwhile, Joanna investigates Julian's girlfriend who works for a rival drug company and finds some suspicious information. Mia offers to save Haverstock by donating her bone marrow but then discovers his true motivation. Sofia pays a visit to a dark character from her past in prison.
As Bowers Pharmaceutical is preparing to have Lyritrol on shelves in 3 weeks, Edward finds out some disturbing news about the new drug. Joanna pursues a lead that ends in a gunfight. Meanwhile, Senator Haverstock reveals his true identity to Mia, and Edward and Julian get into a physical fight at a PR event for Bowers Pharmaceutical, resulting in a big career move for Edward.
The truth about Mia's real mother is revealed when the story is published for everyone to see, ruining her debutant ball and shattering the life she thought she knew. Julian tries to rekindle an old flame who can help them get their new cancer drug on the market. Will and Joanna put their feelings aside to focus on solving Vivian’s murder.
The death of wealthy party girl Vivian Bowers doesn't add up for FBI agent Will Moreno, especially in a family as suspicious as the Bowers. Convinced that the tabloid staple's death was a homicide, he recruits his former SFPD partner and Vivian’s childhood best friend, Joanna Padget Locasto to re-establish ties with the Bowers. Determined to find justice for her estranged best friend, Joanna infiltrates the dynasty she once considered family, and quickly begins to uncover why Vivian's life was very much in danger.