When Denny receives bad news about the state of his Alzheimer's, Alan goes before the Massachusetts Supreme Court to plead for access to an experimental drug that could help his condition. Meanwhile, Jerry and Katie try to help a girl get into Harvard after her SAT scores arouse suspicion, and Catherine Piper returns.
A close call for Denny involving prescription drugs inspires Alan to go after a pharmaceutical company for its unscrupulous advertising tactics. Meanwhile, Carl defends Shirley's 17-year-old granddaughter after she's caught voting illegally, and Jerry and Katie help a girl who was sexually assaulted in a private detention facility.