The Big Mouth kids start high school! Andrew looks inside himself to solve his problem with Pumbaa while dread stops Missy from attending her first day.

During a sleepover, Jay teaches Andrew how to defend himself against bullies. Then, Missy gets overwhelmed while back-to-school shopping with Jessi.

At their first high school party, Andrew discovers his talent for drinking games, Nick hopes for a shot with Danni, and Missy meets a potential rebound.

Andrew takes a liking to his new neighbor — and her mom. Nick wants to be more than Danni's friend, but her entanglement with Travis gets in the way.

Big Mouth goes global for a very special episode as Maury and Connie take a closer look at how kids around the world experience puberty.

As graduation day nears, Nick must decide if he will attend Cobblestones Academy while Andrew goes on an apology tour after being voted "Grossest Human."

While Andrew and Nick follow Judd to Brooklyn to score drugs, Jay gets jealous of Kurt and Lola's relationship, and Jessi oversteps at Matthew's house.

With no distractions, Andrew's schoolwork improves — winning his father's praise. Jessi goes a little too far when trying to emulate cool, mature Leah.

A doctor puts Andrew on testicular rest, Nick asks Jay to help him get in shape for high school and Jessi becomes fascinated by Caitlin's breastfeeding.

With two months left in eighth grade, the incoming freshmen tour their new high school with junior hosts while Jay evades his terrifying brothers.