A heartbroken woman waits for her daughter to come home for the holidays, but she never does; in another state, investigators find a woman's remains, and these two seemingly unrelated incidents come together as investigators finally catch a break.

After a young woman's body is discovered naked in a Minnesota ditch, investigators embark on a decades-long hunt to identify her; meanwhile, over 1,000 miles away, a despairing family refuses to stop looking for the daughter and sister they love.

In 2005, Pamela Knight vanishes on her son's birthday, and, years later, two men find the remains of a woman buried under an abandoned shed.

An unidentified woman's body surfaces in the warm waters of the Gulf of Mexico; meanwhile, a woman vanishes from her new home in Florida, then, nearly 30 years later, both tales are untangled to reveal a story of love, loss, life, and death.

Not long after a jogger discovers a woman’s body off a remote road in Pennsylvania, a family worries when the godmother never shows up to a baptism. A frantic search begins for a missing woman that leads investigators up and down the east coast.

A young woman’s body is found in the Arizona desert, scorched by the sun. Over 2,500 miles away, a young man worries about his missing sister. An investigation into her death begins, and it will take decades to reveal her name and her killer.

The body of a beautiful woman is found in the Pennsylvania woods near Christmas time, and it’s clear her death is no accident. A decade-spanning investigation begins, and officials are determined to discover this woman’s name and bring her home.