When 13-year-old Jennifer Bastian is abducted and murdered in August of 1986, residents of Tacoma panic. This is the second young girl killed in five months. Convinced a predator is loose, police embark on a 32-year inquiry.

When a 30-year-old mother fails to report for duty in Virginia, the Army lists her as AWOL. Her family immediately suspect foul play. They embark on a 13-year quest for answers before an eyewitness blows the case wide open.

A fire in January 2007 in Canton, OH, claims the life of WWII vet Bennie Angelo; a closer look at the crime scene reveals Bennie was dead before the fire, bumping an arson case up to homicide.

In September 1974 in Ohio, 15-year-old Lori Nesson disappeared while walking home from a high school football game after-party. Her naked body is found in a ditch the next day yet is ruled undetermined natural causes. The search for her killer finally begins when the cause of death is changed to homicide 40 years later.

Landlord Bruce Blackwood disappears without a trace in March 2006. Though there is no body, the NYPD is sure this is a homicide and they, along with Bruce's brother Ed, spend the next 9 years searching for answers and a killer.

After a young mother's death in 1988 goes unsolved, her older sister promises to solve the crime, no matter how long it takes, so she sets about on a quest for answers to determine who killed the victim in her own home and why.